Thermal Performance Simulation of an LTCC Micro-Reactor for RT-PCR in Detection of SARS-Cov-2 Detection
DOI:
https://doi.org/10.54554/jtec.2022.14.03.005Keywords:
LTCC, Micro-reactor, COVID-19, Polymerase chain reactionAbstract
In present paper, thermal simulation of LTCC based micro-chamber has been performed which is a key part of RT-PCR device. The RT-PCR device plays an important role in SARS-CoV-2 testing. The rRT-PCR system requires three different thermal cycles for DNA amplification which takes part in detection of SARS-CoV-2. The thermal cycle can be equipped using a heater structure in the chamber. A new LTCC based technique to develop micro-chamber has been designed and simulation has been performed using COMSOL to optimize thermal properties. Temperature distribution for a micro-chamber at three different voltages has been simulated. The temperature distribution is more uniform in micro-chamber with a buried metallic layer in comparision to micro-chamber without a metallic layer. The heater and temperature sensor were located outside the reaction chamber. A platinum based pattern as PTC temperature sensor is used in temperature measurement.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Journal of Telecommunication, Electronic and Computer Engineering
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)