Investigation on Anti-Proliferation Properties of Porcupine Bezoar (Hystrix Brachyuran) Extracts Exposed on Hela Cells Lines Combined with Electroporation Technique

Authors

  • Azra Hazwanie Azizulkarim Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, 86400 Batu Pahat, Johor, Malaysia
  • Muhammad Mahadi Abdul Jamil Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, 86400 Batu Pahat, Johor, Malaysia
  • Mohamad Nazib Adon Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, 86400 Batu Pahat, Johor, Malaysia
  • Ridhwan Abdul Wahab Integrated Centre for Research Animal (ICRACU), International Islamic University Malaysia, Kuantan Campus, Bandar Indera Mahkota, 25200, Kuantan, Pahang, Malaysia
  • Tengku Nadzlin Tengku Ibrahim Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, 86400 Batu Pahat, Johor, Malaysia

Keywords:

Cell anti-proliferation, Cell growth, Electroporation, Porcupine bezoar (PB) extract,

Abstract

Electroporation (EP) is a technique whereby the biophysical changes on the cells that induced external highintensity electrical field pulses in order to enhance applications in the medical field. It is a molecular biology technique in order to create pores through a cell wall membrane, boost the permeability of the cell membrane, and support chemicals, drugs or DNA to be imported into Hela cells. While by combining electroporation (EP) technique with porcupine bezoar (PB) extract might reduce the proliferation of HeLa cells because this compound extract has the ability of antiproliferation and also anti-angiogenesis properties for controlling cancer cell growth. This research concentrate on reviewing and analyses the basic concepts and methods of combining electroporation and porcupine bezoar (PB) extract as applied in cancer treatment application. The combination of this technique might be a new alternative for anti-cancer treatment. The combination of this technique might be a new way for anticancer treatment.

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Published

2018-05-31

How to Cite

Azizulkarim, A. H., Abdul Jamil, M. M., Adon, M. N., Abdul Wahab, R., & Tengku Ibrahim, T. N. (2018). Investigation on Anti-Proliferation Properties of Porcupine Bezoar (Hystrix Brachyuran) Extracts Exposed on Hela Cells Lines Combined with Electroporation Technique. Journal of Telecommunication, Electronic and Computer Engineering (JTEC), 10(1-17), 5–9. Retrieved from https://jtec.utem.edu.my/jtec/article/view/4155

Issue

Vol. 10 No. 1-17: Recent Trends in Biomedical Engineering Systems and Technologies II

Section

Articles

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