@article{Kulhari_Suri_Ahmad_Yupapin_Ray_2022, title={Thermal Performance Simulation of an LTCC Micro-Reactor for RT-PCR in Detection of SARS-Cov-2 Detection}, volume={14}, url={https://jtec.utem.edu.my/jtec/article/view/6213}, abstractNote={<p>In present paper, thermal simulation of LTCC based micro-chamber has been performed which is a key part of RT-PCR device. The RT-PCR device plays an important role in SARS-CoV-2 testing. The rRT-PCR system requires three different thermal cycles for DNA amplification which takes part in detection of SARS-CoV-2. The thermal cycle can be equipped using a heater structure in the chamber. A new LTCC based technique to develop micro-chamber has been designed and simulation has been performed using COMSOL to optimize thermal properties. Temperature distribution for  a micro-chamber at three different voltages has been simulated. The temperature distribution is more uniform in  micro-chamber with a buried metallic layer in comparision to micro-chamber without a metallic layer. The heater and temperature sensor were located outside the reaction chamber. A platinum based pattern as PTC temperature sensor is used in temperature measurement.</p>}, number={3}, journal={Journal of Telecommunication, Electronic and Computer Engineering (JTEC)}, author={Kulhari, Lokesh and Suri, Nikhil and Ahmad, Badrul Hisham and Yupapin, Preecha and Ray, Kanad}, year={2022}, month={Sep.}, pages={29–34} }